A novel method for synthesis of a chiral amine borane is described and selective reductions of carbonyl compounds with the amine borane are investigated.
ChemInform Abstract: Synthesis and Reduction Ability of Borane Complexes of 2-Aminopyridine Derivative Having a Chiral Center at the Amino Nitrogen.
β Scribed by Y. YAMAGUCHI; A. TAKADA; Y. OKAMOTO
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 30 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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Optically active allenyltitanium [cf. (III)], generated from propargyl alcohol derivatives in solution, undergoes regioselective hydrolysis and halogenolysis to give the alkyne (IV) and the chloride (V) with excellent degree of chiral transfer. This approach is also successfully applied to the synth
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