Sulphamethoxazole hydroxylamine (SMX-NHOH) and nitroso sulphamethoxazole (SMX-NO) were prepared bv a modified literature procedure. SMX-NO produced a complex set of unstable intermediates with sulphur nucleophiles, but did not react with amino containing compounds. No reactions were observed between
β¦ LIBER β¦
ChemInform Abstract: Synthesis and Reactions of Nitroso Sulfamethoxazole with Biological Nucleophiles: Implications for Immune Mediated Toxicity.
β Scribed by D. J. NAISBITT; P. M. O'NEILL; M. PIRMOHAMED; B. K. PARK
- Book ID
- 112040422
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 28 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0931-7597
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