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ChemInform Abstract: Synthesis and Reactions of Esters of 2-Oxo-3-cyanotri(tetra)methylene- 1,2-dihydroisonicotinic and 2-Amino-3-ethoxycarbonyl-5,6-tri(tetra) methyleneisonicotinic Acid.

✍ Scribed by T. A. SMIRNOVA; M. YU. GAVRILOV

Book ID: 112039205
Publisher: John Wiley and Sons
Year: 2010
Weight: 31 KB
Volume: 27
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199643126

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ChemInform Abstract: Synthesis of Methyl

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ChemInform Abstract: Synthesis and Exchange Reactions of 5-Alkyl-2-oxo-6-thioxo-1,2,3,6-Tetrahydropyrimidine-4-carboxylic Acids.

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Synthesis and Exchange Reactions of 5-Alkyl-2-oxo-6-thioxo-1,2,3,6-Tetrahydropyrimidine-4-carboxylic Acids. -The title compounds are prepared as potential dihydroorotase inhibitors. H/D-exchange studies establish a high tendency towards epimerization at C-5. No epimerization is observed under physi