ChemInform Abstract: Synthesis and Properties of 5-(4,6-Diphenyl-2-pyrimidin-2-yl)-1,2,4-triazolin-3-thione and Its Derivatives.

✍ Scribed by G. MEKUSKIENE; P. GAIDELIS; P. VAINILAVICIUS

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 31 KB
• Volume: 29
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199821145

✦ Synopsis

Synthesis and Properties of 5-(4,6-Diphenyl-2-pyrimidin-2-yl)-1,2,4triazolin-3-thione and Its Derivatives.

-The title compound (IV) is synthesized by alkali-mediated cyclization of acylthiosemicarbazide (III) and transformed into pyrimidine-substituted thiazolotriazoles (VIII). Some of the synthesized compounds, e.g. (III), (IV), and (VIIIa), possess a weak antiinflam-