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ChemInform Abstract: Synthesis and Phosphatase Inhibitory Activity of Analogues of Sulfircin.

โœ Scribed by R. E. CEBULA; J. L. BLANCHARD; M. D. BOISCLAIR; K. PAL; N. J. BOCKOVICH

Publisher
John Wiley and Sons
Year
2010
Weight
34 KB
Volume
28
Category
Article
ISSN
0931-7597

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## Dedicated to Professor Dieter Seebach on the occasion of his 65th birthday Gelastatin A and B, isolated from culture broth of Westerdykella multispora F 50733, have been reported to exhibit MMP-inhibitory activities at a sub-micromolar level. In an effort to exploit this lead, we synthesized ge