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ChemInform Abstract: Synthesis and Pharmacological Evaluation of 5,6-Dihydrobenzo(f) cinnolin-2(3H)ones Analogues of Antihypertensive and Antiaggregating Benzo(h)cinnolinones.

✍ Scribed by G. A. PINNA; M. M. CURZU; P. FRAGHI; E. GAVINI; M. D'AMICO

Publisher: John Wiley and Sons
Year: 2010
Weight: 31 KB
Volume: 28
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199717149

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✦ Synopsis

Synthesis and Pharmacological Evaluation of 5,6-Dihydrobenzo(f ) cinnolin-2(3H)ones Analogues of Antihypertensive and Antiaggregating Benzo(h)cinnolinones.

-The new benzo(h)cinnolinones (IX) and (X) show weaker hypotensive and antihypertensive activity, but more inhibition activity on collagen-induced platelet aggregation than the model compound (XI).

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