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ChemInform Abstract: Synthesis and Odor of Chiral Partial Structures of Khusimone. Part 3.

โœ Scribed by H. SPREITZER; A. PICHLER; W. HOLZER; C. SCHLAGER


Publisher
John Wiley and Sons
Year
2010
Weight
26 KB
Volume
29
Category
Article
ISSN
0931-7597

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โœฆ Synopsis


Synthesis and Odor of Chiral Partial Structures of Khusimone. Part 3. -Khusimone (I) is one of the main odor-donating compounds of vetiver oil. For structure-odor relationship studies the bicyclic partial structure (II) missing the methano bridge is considered. Unexpectedly, (II) cannot be obtained since epimerization favors (III). Compound (III) exhibits an intense woody and camphoraceous odor, but lacks the typical vetiver odor. -(SPREITZER, H.;


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Synthesis and odor of chiral partial str
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Several stereoisomeric, monocyclic analogs of (-)-โค-vetivone (1), one of the main constituents of vetiver oil, were studied to examine if the olfactory properties of (-)-โค-vetivone (1) could be reproduced from these structurally simpler, synthetically accessible compounds. The effects of diastereome

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