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ChemInform Abstract: Synthesis and Molecular Modeling Studies of Antiinflammatory Active 1H-Pyrrolizine-5-carboxamides.

✍ Scribed by Flora F. Barsoum


Publisher
John Wiley and Sons
Year
2011
Weight
32 KB
Volume
42
Category
Article
ISSN
0931-7597

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Synthesis and Molecular Modeling Studies
✍ Flora F. Barsoum πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 300 KB

## Abstract A variety of __N__‐aryl‐7‐cyano‐2,3‐dihydro‐1__H__‐pyrrolizine‐5‐carboxamides **5**, **6**, **8**, and **9** were synthesized __via__ reaction of the 2‐amino derivatives **4** with acid chlorides and aromatic aldehydes. Meanwhile, **4a**,**b** were obtained through the reaction of 2‐pyr