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ChemInform Abstract: Synthesis and in vitro Evaluation of the Antifungal Activities of Dihydropyrimidinones.

✍ Scribed by Okram Mukherjee Singh; Sarangthem Joychandra Singh; Mutum Babita Devi; Laitonjam Nalini Devi; Nameirakpam Irabanta Singh; Sang-Gyeong Lee


Publisher
John Wiley and Sons
Year
2009
Weight
24 KB
Volume
40
Category
Article
ISSN
0931-7597

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## Abstract __Herein we describe the scalable diastereoselective and enantioselective syntheses of eight enantiomers of hydroxy metabolites of saperconazole. The inβ€…vitro antifungal activity of the eight stereoisomers (compounds **1**–**8**) was compared against a broad panel of__ Candida__spp. (__