ChemInform Abstract: Synthesis and Enzymic Effect of Some Novel 1,2-Dihydro-3-(triazin-5/6-yl)benzo[h]quinolin-2-one Derivatives.
β Scribed by M. M. Ismail
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 34 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0931-7597
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## Synthesis of 2H-Benzo(2,3-g)pyridazino(4,5-d,e)quinolin-3-one Derivatives. -Treatment of the benzo(g)quinolinequinones (I), (III), and (IV) with hydrazine affords the corresponding title compounds (II) and (V), whereas reaction of (Ih) with (VI) yields the hydrazone (VII). -
## Abstract (__R__)β5β(diallylamino)β5,6βdihydroβ4__H__βimidazo[4,5,1β__ij__]quinolinβ2(1__H__)βone (__12b__) was prepared in 9% overall yield from 3βaminoquinoline. Reaction of __12b__ in ethyl acetate with tritium gas in presence of a 5% platinum on carbon catalyst afforded a mixture of (__R__)β5