ChemInform Abstract: Synthesis and DNA Binding Properties of Bis-9-acridinyl Derivatives Containing Mono-, Di-, and Tetra-Viologen Units as a Connector of Bis- Intercalators.

Synthesis and DNA binding properties of

Synthesis and DNA binding properties of bis-9-acridinyl derivatives containing mono-, di-and tetra-viologen units as a connector of bis-intercalators

✍ Shigeori Takenaka; Hirotaka Sato; Toshihiro Ihara; Makoto Takagi 📂 Article 📅 1997 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 312 KB

## Abstract Bis‐9‐acridinyl derivatives 1–3 containing mono‐, di‐and tetra‐viologen units as a rigid connector were synthesized. The binding studies of these intercalators for natural and synthetic DNAs showed that these compounds act as bis‐intercalators where viologen moieties lie in the minor gr