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ChemInform Abstract: Synthesis and Cytotoxicity of Natural (+)-Duocarmycin A and Its Three Possible Stereoisomers.

โœ Scribed by K. NAKATANI; Y. FUKUDA; S. TERASHIMA


Book ID
112021307
Publisher
John Wiley and Sons
Year
2010
Weight
26 KB
Volume
26
Category
Article
ISSN
0931-7597

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๐Ÿ“œ SIMILAR VOLUMES


Synthetic studies on duocarmycin. 2. Syn
โœ Yasumichi Fukuda; Kazuhiko Nakatani; Shiro Terashima ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 922 KB

The title synthesis was achieved by featuring the optical resolution of two types of the tricyclic intermediates and the synthetic scheme established in the synthesis of racemic compounds. In vitro cytotoxicity assay against P388 murine leukemia obviously showed that the absolute configuration of cy