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ChemInform Abstract: Synthesis and Characterization of Some Coumarins with Two Hydroxy or Methoxy Substituents.

✍ Scribed by Yagamare Fall; Lourdes Santana; Eugenio Uriarte


Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
33
Category
Article
ISSN
0931-7597

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## Abstract The first synthesis of the 6‐hydroxy‐4‐methoxycoumarin (**5**) was carried out in 25 % overall yield from 6‐methoxy‐4‐hydroxycoumarin (**1**) by hydrolysis of the methoxy group and subsequent selective methylation of the hydroxyl group at position 4. The ^1^H and ^13^C NMR data of compo

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## Abstract Coumarin analogues bearing an acyl function at position 3, halogens at position 6, substituted or unsubstituted benzyloxy moieties at position 7, and a methyl group at position 8, are synthesized.