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ChemInform Abstract: Synthesis and Biological Evaluation of Novel n-[3-(4-Phenylpiperazin-1-yl)-propyl]-carboxamide Derivatives.

✍ Scribed by Zhiyong Weng; Yanping Gao; Jiankang Zhang; Xiaowu Dong; Tao Liu

Publisher: John Wiley and Sons
Year: 2011
Weight: 32 KB
Volume: 42
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.201123155

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## Abstract For Abstract see ChemInform Abstract in Full Text.

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## Abstract A series of novel 3‐(coumarin‐4‐yl)tetrahydroisoxazoles **5a,b, 7, 9** and 3‐(coumarin‐4‐yl)dihydropyra‐zoles **13a‐d, 14,15a,b** were synthesized from coumarin‐4‐carboxaldehyde **1** __via__ the intermediate __N__‐methyl nitrone **3** and __N__‐phenyl or __N__‐methyl hydrazones **11a,b