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ChemInform Abstract: Synthesis and Biological Evaluation of 2-Aminoisonicotinic Acid Analogues as HIF-1α Inhibitors.

✍ Scribed by Yan Xia; Misun Won; Jung Eun Kang; Song-Kyu Park; Kiho Lee; Hwan-Mook Kim; Kyeong Lee

Publisher
John Wiley and Sons
Year
2011
Weight
28 KB
Volume
42
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

A series of 2‐aminoisonicotinic acid derivatives such as (I) and (II) is synthesized and evaluated for their in vitro HIF‐1 inhibitory activity.

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