Synthesis and Binding Properties of a Ma
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James Dowden; Peter D. Edwards; Stephen S. Flack; Jeremy D. Kilburn
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Article
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1999
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John Wiley and Sons
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English
โ 232 KB
๐ 2 views
Macrocyclic receptor 1 has been synthesised, as a racemate and as a single enantiomer, utilising a Stille coupling for the formation of the biphenyl portion and a macrolactamisation as the final step. The binding properties for the racemic and the homochiral macrocycle with amino acid and dipeptide