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ChemInform Abstract: Synthesis and Antitumor Activities of Methyl 2-O-Aryl-6-O-aryl′-D-glucopyranosides.

✍ Scribed by Hefang Shi; Bingcheng Zhou; Wenwen Li; Zhimin Shi; Biao Yu; Renxiao Wang


Publisher
John Wiley and Sons
Year
2010
Weight
24 KB
Volume
41
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

A new synthetic method to introduce bulky aryl groups at both the 2‐O‐ and 6‐O‐position on D‐glucopyranoside is developed.


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Syntheses of Methyl 2-O-, 3-O-and 6-O-(2'-Hydroxypropyl)-α-Dglucopyranosides. -In order to determine the position of substitution of hydroxypropyl groups in lightly modified starch the title compounds (I)-(III) are prepared in a few steps by conventional procedures using epibromohydrine.