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ChemInform Abstract: Synthesis and Antiproliferative Evaluation of 5-oxo and 5-thio Derivatives of 1,4-Diaryl Tetrazoles.

โœ Scribed by Aditya S. Gundugola; Kusum Lata Chandra; Elisabeth M. Perchellet; Andrew M. Waters; Jean-Pierre H. Perchellet; Sundeep Rayat


Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
41
Category
Article
ISSN
0931-7597

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A green and convenient approach to the synthesis of novel 4,7-diaryl-2-oxo(thio)-1,2,3,4,5,6,7,8-octahydroquinazoline-5-one derivatives from appropriate aromatic aldehydes and 5-aryl-1,3-cyclohexanedione with urea or thiourea in the presence of dilute HCl as catalyst in water is described. This meth