ChemInform Abstract: Synthesis and Antiproliferative Activity of Multisubstituted N-Fused Heterocycles Against the Hep-G2 Cancer Cell Line.
β Scribed by Yong-Miao Shen; Peng-Cheng Lv; Ming-Zhu Zhang; Hui-Quan Xiao; Li-Ping Deng; Hai-Liang Zhu; Chen-Ze Qi
- Publisher
- John Wiley and Sons
- Year
- 2011
- Weight
- 34 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
The [3 + 2] cycloaddition reactions of imidazolium ylides and thiazolium ylides with alkenes followed by oxidative aromatization of the primary cycloadducts using the mild oxidant tetrakispyridinecobalt(II) dichromate in oneβpot lead to pyrrolo[1,2βa]imidazole and pyrrolo[2,1βb]thiazole derivatives, respectively.
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