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ChemInform Abstract: Synthesis and Antimicrobial Activity in vitro of New Amino Acids and Peptides Containing Thiazole and Oxazole Moieties.

โœ Scribed by Mincho Stanchev; Svoboda Tabakova; Georgi Videnov; Evgeny Golovinsky; Guenther Jung


Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
30
Category
Article
ISSN
0931-7597

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Synthesis of thiazole, imidazole and oxa
โœ Ivanka G. Stankova; Georgi I. Videnov; Evgeny V. Golovinsky; Guenther Jung ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 94 KB ๐Ÿ‘ 2 views

Novel 5-ring heterocyclic building blocks are synthesized. These can be incorporated into analogs of peptide antibiotics such as microcin B17, which is a potent DNA-gyrase inhibitor that exhibits eight thiazole and oxazole moieties. In particular, the syntheses of imidazole and bisoxazole amino acid