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ChemInform Abstract: Synthesis and Antileishmanial Activity of Some Chromon-8-ylalkanoic Acids and Their Methyl Esters.

✍ Scribed by S. P. BHATTI; C. P. GARG; R. P. KAPOOR; A. KAPIL; S. SHARMA

Publisher
John Wiley and Sons
Year
2010
Weight
40 KB
Volume
29
Category
Article
ISSN
0931-7597

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✦ Synopsis

Synthesis and Antileishmanial Activity of Some Chromon-8-ylalkanoic Acids and Their Methyl Esters. -A variety of new chromonylalkanoic acids (X) (9 examples) and their methyl esters (IX) are synthesized involving the facile Ph-I(O-Ac) 2 mediated 1,2-aryl migration [(VII)β†’(IX)] as the key step. Acid (Xc) is found to possess promising antileishmanial activity. -(BHATTI, S.

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