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ChemInform Abstract: Synthesis and Anticonvulsant Activity of Some N-Phenyl-2-phthalimidoethanesulfonamide Derivatives.

✍ Scribed by Ozlem Akgul; Fatma Sultan Kilic; Kevser Erol; Varol Pabuccuoglu


Publisher
John Wiley and Sons
Year
2008
Weight
27 KB
Volume
39
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

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## Abstract A series novel of __N__‐(2‐hydroxyethyl)amide derivatives was synthesized and screened for their anticonvulsant activities by the maximal electroshock (MES) test, and their neurotoxicity was evaluated by the rotarod test (Tox). The maximal electroshock test showed that __N__‐(2‐hydroxye