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ChemInform Abstract: Synthesis and Anticonvulsant Activities of 3,3-Dialkyl- and 3-Alkyl-3- benzyl-2-piperidinones (δ-Valerolactams) and Hexahydro-2H-azepin- 2-ones (.epsilon.-Caprolactams).

✍ Scribed by P. A. REDDY; K. E. WOODWARD; S. M. MCILHERAN; B. C. H. HSIANG; T. N. LATIFI; M. W. HILL; S. M. ROTHMAN; J. A. FERRENDELLI; D. F. COVEY

Book ID: 101844953
Publisher: John Wiley and Sons
Year: 2010
Weight: 32 KB
Volume: 28
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199717133

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✦ Synopsis

Synthesis and Anticonvulsant Activities of 3,3-Dialkyl-and 3-Alkyl-3benzyl-2-piperidinones (δ-Valerolactams) and Hexahydro-2H-azepin-2-ones (.epsilon.-Caprolactams).

-A series of δ-valerolactam, such as (VI) or (X), and .epsilon.-caprolactam derivatives (XI) are prepared and evaluated as anticonvulsants in mice. The most effective compound is (X). In contrast, none of the compounds (XI) has anticonvulsant effect. -(REDDY,

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Synthesis and Anticonvulsant Activities

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✍ Reddy, P. Amruta; Woodward, Karen E.; McIlheran, Sarah M.; Hsiang, Bonnie C. H.; 📂 Article 📅 1997 🏛 American Chemical Society 🌐 English ⚖ 241 KB

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Synthesis and Anticonvulsant Activity of 2(3H)-Benzoxazolone and 2(3H)-Benzothiazolone Derivatives. -The most active derivatives among 45 title compounds are (II) and (III). -(UCAR, H.; VAN DER-

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Microwave synthesis and anticonvulsant activity of new 3-benzyl-1,2,3-benzotriazin-4(3H)-ones

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## Abstract Several 3‐benzyl‐1,2,3‐benzotriazin‐4(3__H__)‐ones 1 were prepared by alkylation of 1,2,3‐benzotriazin‐4(3__H__)‐one with benzyl halides in dimethylformamide in a microwave oven in moderate yields. Accompanying 1 were minor amounts of products believed to be the __O__‐alkylated derivati

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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v