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ChemInform Abstract: Synthesis and Antibacterial Activity of Dual-Action Agents of a β-Lactam Antibiotic with Cytotoxic Agent Mitozolomide or Temozolomide.

✍ Scribed by Yongfeng Wang; Peter Lambert; Linxiang Zhao; Danni Wang


Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
33
Category
Article
ISSN
0931-7597

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Synthesis, Pharmacokinetics, and Biological Activity of a Series of New Pyridonecarboxylic Acid Antibacterial Agents Bearing a 5-Fluoro-2-pyridyl Group or a 3-Fluoro-4-pyridyl Group at N-1. -A variety of new quinolones bearing fluorinated pyridyl groups at N1 ( cf. (VIII), (IX); 18 examples) are syn