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ChemInform Abstract: Synthesis and anti-HIV Evaluation of New Acyclic Phosphonate Nucleotide Analogues and Their Bis(sate) Derivatives.

✍ Scribed by Hua Li; Joon Hee Hong

Publisher: John Wiley and Sons
Year: 2010
Weight: 32 KB
Volume: 42
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.201104216

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## Abstract The cyclopentane moiety is synthesized from aldehyde (I) through a de novo acyclic synthetic route using reiterative Grignard additions and ring‐closure metathesis to produce the required synthon (VIII).