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ChemInform Abstract: Synthesis and Anti-Hepatitis B Virus Activity of Some 2,3-Dihydroxyprop-1-yl Unnatural Hetaryls.

✍ Scribed by El Sayed H. El Ashry; Adel A.-H. Abdel-Rahman; Nagwa Rashed; Hanaa A. Rasheed

Publisher: John Wiley and Sons
Year: 2010
Weight: 27 KB
Volume: 30
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199949196

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✦ Synopsis

Synthesis and Anti-Hepatitis B Virus Activity of Some 2,3-Dihydroxyprop-1-yl Unnatural Hetaryls.

-Seven nucleoside analogues of type (IV) are prepared and tested for their inhibition activities against Hepatitis B virus (HBV). Compounds (IVa) and (IVc) show the highest replication inhibition and low cytotoxicity. -(EL ASHRY,

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