ChemInform Abstract: Syntheses via Vinyl Sulfones. Part 75. Triflone Chemistry. Part 10. Scope and Limitations of Functionalized Acetylenic Triflones in the Direct Alkynylation of C-H Bonds.

✍ Scribed by J. XIANG; W. JIANG; P. L. FUCHS

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 31 KB
• Volume: 28
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199751081

✦ Synopsis

Syntheses via Vinyl Sulfones. Part 75. Triflone Chemistry. Part 10. Scope and Limitations of Functionalized Acetylenic Triflones in the Direct Alkynylation of C-H Bonds.

-Cyclic ethers, sulfides, and hydrocarbons (I) react with acetylenic trifluoromethyl sulfones ("triflones") to provide the products (III) of radical C-H alkynylation. Alkynes bearing propargylic oxygen cannot be prepared, but silyl or ethers and chlorides in remote positions are tolerated. Furthermore, crown ethers (cf. (IV)) are successfully monofunctionalized. -(XIANG,