ChemInform Abstract: Syntheses of Some Polyunsaturated Trifluoromethyl Ketones as Potential Phospholipase A2 Inhibitors.
β Scribed by Anne Kristin Holmeide; Lars Skatteboel
- Publisher
- John Wiley and Sons
- Year
- 2000
- Weight
- 27 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0931-7597
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Synthesis of Substituted Benzoyl Acrylic Acids as Potential Inhibitors of Phospholipase A 2 . -Acylation of long-chain alkylbenzenes with maleic anhydride derivatives under Friedel-Crafts conditions provides access to benzoylacrylic acids [cf. (III)/(IV), (VIII)], which are evaluated for their abili
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