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ChemInform Abstract: Syntheses of rac- and Optically Active 2-Alkyl-γ-butyrolactones and 2-Alkyl-cyclobutanones.

✍ Scribed by A. KRIEF; A. RONVAUX; A. TUCH


Publisher
John Wiley and Sons
Year
2010
Weight
31 KB
Volume
29
Category
Article
ISSN
0931-7597

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✦ Synopsis


Syntheses of rac-and Optically Active 2-Alkyl-γ-butyrolactones and 2-Alkyl-cyclobutanones.

-A method previously reported from the authors is found to be superior to a method reported by Fukumoto with respect to the second step of the process, i.e. the rearrangement of diols like (I) to cyclobutanones. Optically active butyrolactones are also directly available from diols. Alkenes like (IV) are successfully transformed to racemic lactones in the presence of trifluoroperacetic acid generated in situ. -(KRIEF, A.;


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