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ChemInform Abstract: Sulfahydantoins as Tripeptide Constraints: Synthesis and Structure of Chiral Substituted 3-Oxo-1,2,5-thiadiazolidine 1,1-Dioxides

✍ Scribed by Sihem Boudjabi; Georges Dewynter; Normand Voyer; Loic Toupet; Jean-Louis Montero

Publisher: John Wiley and Sons
Year: 2010
Weight: 28 KB
Volume: 30
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199947208

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A sulfahydantoin (3-oxo-1,2,5-thiadiazolidine 1,1-dioxides) absolute configuration of the chiral centers for the derivative L-Phe-D-Ala, a congener of the series, was established by X-motif is used as a new type of peptidic constraint to lock two consecutive amide nitrogens by a sulfonyl bridge. The

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