A series of dialkyl 1-(N-substituted amino)-2,2,2-trifluoroethylphosphonates was synthesized by Arbuzovtype reactions involving an N-substituted trifluoromethylimidoyl chloride and the appropriate trialkyl phosphite. The resulting Cβ«Χ‘β¬N bond was successfully hydrogenated by NaBH 4 CN treatment. The
ChemInform Abstract: Studies on Organophosphorus Compounds. Part 101. A Facile Synthetic Route to Trifluoromethylated Aminophosphonic Acids and Phosphonopeptides.
β Scribed by C. YUAN; Y. ZHANG; W. LUO; Z. YAO
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 32 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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