ChemInform Abstract: Studies Directed Towards the Regioselective Carboxylation of the 4-Oxo- 4,5,6,7-tetrahydrothieno(3,2-c)pyridine Ring System.
β Scribed by W. HALCZENKO; G. D. HARTMAN
- Book ID
- 112035324
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 30 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0931-7597
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## Abstract The PictetβSpengler reaction is performed as a oneβpot procedure by condensing thienylethylamine (I) with carbonyl compounds (II), followed by treatment of the in situ formed imines with aceticβformic anhydride (III) to produce a formyliminium ion, which upon treatment with TFA cyclizes