ChemInform Abstract: Structure-Activity Relationships of Some 1,4-Benzodioxane Arylpiperazine Derivatives as α-Blocking Agents.

✍ Scribed by S. CORSANO; G. STRAPPAGHETTI; R. SCAPICCHI; G. MARUCCI

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 30 KB
• Volume: 28
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199706143

✦ Synopsis

Structure-Activity

Relationships of Some 1,4-Benzodioxane Arylpiperazine Derivatives as α-Blocking Agents.

-A series of novel 1,4-benzodioxane derivatives (III) (8 examples) are synthesized and evaluated for their blocking activity on α-adrenoceptors. Structure-activity relationships are discussed.

-(CORSANO, S.; STRAPPAGHETTI, G.;