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ChemInform Abstract: Strain-Promoted 1,3-Dipolar Cycloadditions of Diazo Compounds with Cyclooctynes.

✍ Scribed by Joseph Moran; Craig S. McKay; John Paul Pezacki

Publisher
John Wiley and Sons
Year
2011
Weight
25 KB
Volume
42
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

Reactions of cyclooctyne with diazoalkanes (IVa) and (VI) containing electron‐donating groups proceed with very high reaction rates which are comparable to those obtained in analogous cycloaddition reactions employing azides or nitrones.

πŸ“œ SIMILAR VOLUMES

1,3-Dipolar cycloaddition reactions of c
1,3-Dipolar cycloaddition reactions of cyclooctyne with pyridinium dicynomethylides
✍ Kiyoshi Matsumoto; Ryuji Ohta; Takane Uchida; Hiroyasu Nishioka; Maki Yoshida; A πŸ“‚ Article πŸ“… 1997 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 387 KB

## Abstract Cyclooctyne smoothly underwent 1,3‐dipolar cycloaddition with pyridinium dicyanomethylides to afford the corresponding indolizines (8‐cyario‐7‐azatricyclo[7.6.0.0^2,7^]pentadeca‐1,3,5,8‐tetraenes) in excellent yields.