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ChemInform Abstract: Steroidal Cyclobutanones. Part 5. The Baeyer-Villiger Rearrangement of α-Substituted β-Spirocyclobutanones.

✍ Scribed by Z. PARYZEK; K. BLASZCZYK


Book ID
112022471
Publisher
John Wiley and Sons
Year
2010
Weight
35 KB
Volume
26
Category
Article
ISSN
0931-7597

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Steroidal cyclobutanones, V. the baeyer-
✍ Paryzek, Zdzislaw ;Blaszczyk, Krzysztof 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 477 KB

## Abstract The reaction of the steroidal spiro‐α,α‐dichlorocyclobutanone 1 carried out in basic H~2~O~2~/MeOH/THF solution proceeds with __cine__ substitution leading to the intermediate α‐chloro‐α‐methoxycyclobutanone 7 followed by the Baeyer‐Villiger rearrangement giving the spiro‐α‐chloro‐γ‐met