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ChemInform Abstract: Stereospecific Ring Expansion of Chiral Vinyl Aziridines.

✍ Scribed by Matthew Brichacek; Mauricio Navarro Villalobos; Alexandra Plichta; Jon T. Njardarson


Publisher
John Wiley and Sons
Year
2011
Weight
38 KB
Volume
42
Category
Article
ISSN
0931-7597

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Preparation and Ring-Opening Reactions of N-Diphenylphosphinyl Vinyl Aziridines. -LDA-Lithiation of allyl bromide (I) followed by ZnCl2 generates Ξ± -bromo allyllithium which reacts with phosphinyl aldimines to form mainly trans-or cis-aziridines depending on the substituent R. The arylated trans-der