𝔖 Bobbio Scriptorium
✦   LIBER   ✦

ChemInform Abstract: Stereoselectivity in the Double Reductive Alkylation of Pyrroles: Synthesis of cis-3,4-Disubstituted Pyrrolidines.

✍ Scribed by Timothy J. Donohoe; Rakesh R. Harji; Rick P. C. Cousins

Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
30
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

ChemInform Abstract: Stereoselective Syn
ChemInform Abstract: Stereoselective Synthesis of trans-(2R,3S)- and cis-(2R,3R)-Disubstituted Pyrrolidines.
✍ Young-Ah Kim; Sang-Mi Oh; So-Yeop Han πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 32 KB πŸ‘ 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v

ChemInform Abstract: Synthesis of (.+-.)
ChemInform Abstract: Synthesis of (.+-.)-Oxohexahydrofuro[3,2-b]pyrroles (Pyrrolidine-trans-lactones) via a Reductionβ€”Alkylation Protocol.
✍ Simon J. F. Macdonald; John G. Montana; Doreen M. Buckley; Michael D. Dowle πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 35 KB

Synthesis of (Β±)-Oxohexahydrofuro [3,2-b]pyrroles (Pyrrolidine-translactones) via a Reduction-Alkylation Protocol. -Hydride reduction of the cyclic keto-ester (I) gives mainly the cis-lactone (II). However, immediate hydroxyl inversion with benzoic acid prior to lactonization gives the trans-product