✦ LIBER ✦
ChemInform Abstract: Stereoselective Transformation of Enantiopure Cyclohexenol into cis- Hydrindan. An Enantioselective Formal Total Synthetic Route to (+)- Pumiliotoxin C.
✍ Scribed by M. TOYOTA; T. ASOH; M. MATSUURA; K. FUKUMOTO
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 32 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Stereoselective Transformation of Enantiopure Cyclohexenol into cis-Hydrindan. An Enantioselective Formal Total Synthetic Route to (+)-Pumiliotoxin C. -Starting from the known chiral acid (I) the biologically interesting title compound (IX) is synthesized. Key step in this approach is the cyclization to the cis-hydrindan (VI) under mild conditions without the high dilution technique and the long reaction time required in the radical step. -(TOYOTA, M.;