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ChemInform Abstract: Stereoselective Synthesis of (-)-α-Kainic Acid and (+)-α- Allokainic Acid via Trimethylstannyl-Mediated Radical Carbocyclization and Oxidative Destannylation.

✍ Scribed by S. HANESSIAN; S. NINKOVIC


Publisher
John Wiley and Sons
Year
2010
Weight
36 KB
Volume
28
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Stereoselective Syn
✍ M. D. BACHI; N. BAR-NER; A. MELMAN 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 38 KB 👁 1 views

Stereoselective Synthesis of (±)-α-Kainic Acid Using Free Radical Key Reactions. -The title compound (XI) is obtained via two routes from the highly substituted isocyanide and the isothiocyanate (XII) via the common intermediate (IX). In both routes the key synthons (cf. (IV) and (XIV)) are obtained