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ChemInform Abstract: Stereoselective Synthesis of Methylene Phosphonate Analogues of Thymidine 3′-Phosphate and 2′-Deoxyuridine 3′-Phosphate via Intramolecular N-Glycosylation Reaction of Thioglycosides.

✍ Scribed by Tsutomu Yokomatsu; Takanori Shimizu; Tomoyuki Sada; Shiroshi Shibuya


Publisher
John Wiley and Sons
Year
2010
Weight
31 KB
Volume
30
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Stereoselective Syn
✍ J. LLUIS; M. I. MATHEU; S. CASTILLON 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 34 KB 👁 1 views

Stereoselective Synthesis of 2',3'-Dideoxy-nucleosides via Intramolecular Glycosylation of Phenyl 1-Seleno-glycosides. Synthesis of 2',3'-Dideoxythymidine. -The intramolecular glycosylation of the coupling products (III) is examined. However, treatment with AgO-Tf and NaOH results only in the isol