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ChemInform Abstract: Stereoselective Synthesis of Functionalized Five-, Six- and Seven-Membered Heterocyclic Systems via Intramolecular Cycloaddition of C-Alkenyl Nitrones and Nitrile Oxides

✍ Scribed by U. CHIACCHIO; A. RESCIFINA; G. ROMEO


Publisher
John Wiley and Sons
Year
2010
Weight
25 KB
Volume
29
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Stereochemistry. Pa
✍ I. N. N. NAMBOOTHIRI; A. HASSNER; H. E. GOTTLIEB πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 32 KB

Strategy for the Construction of Functionalized Five-and Six-Membered Carbocycles. -Conjugate addition of the Grignard reagents (II) and (IV) to the nitro olefins (I) leads to the intermediate formation of nitronates, which are trapped as silyl nitronates and subsequently cyclized by intramolecular