ChemInform Abstract: Stereoselective Synthesis of Freidinger Lactams Using Oxaziridines Derived from Amino Acids.
β Scribed by M. S. WOLFE; D. DUTTA; J. AUBE
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 30 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Stereoselective Synthesis of Freidinger Lactams Using Oxaziridines Derived from Amino Acids.
-Enantiopure Freidinger lactams, e.g. (IV), (VII), and (X), are synthesized via the corresponding oxaziridines. Although the preparation of the chiral spirocyclic oxaziridines often leads to more than one diastereomer, separation is not necessary in some cases, since the mixtures converge upon the same lactam. The utility of this method is illustrated by the synthesis of potential inhibitors of angiotensin-converting enzyme. -(WOLFE, M.
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v