Irradiation of fl--aminopropiophenones l leads to the formation of 2-aminocyclopropanols 2 which can undergo oxidative ring opening to give enaminones 3. The regioselectivity of cyclopropanol formation of the a-benzyl substituted 1 is determined by the preferred charge transfer interaction between t
ChemInform Abstract: Stereoselective Photocyclization to 2-Aminocyclopropanols by Photolysis of β-Aminoketones and Oxidative Ring Opening to Enaminones.
✍ Scribed by W. WEIGEL; S. SCHILLER; H.-G. HENNING
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 33 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0931-7597
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Stereoselective Cyclopropanation and Ring-Opening: Application to the Synthesis of Pure (S)-2-Methyl-3-arylpropylamines. -A short synthesis (6 steps) of the (S)-enantiomers (I) and (II) of the fungicides fenpropimorph and fenpropidine is presented. The required trans-isomers (VI) of the cyclopropan