An asymmetric synthesis of mgio-and stem3sdectively deutmum-labelled L-lcucine was eaamined using 4-hydmxy-L-proline as a chiral template. An enoi trifl~te of 4-oxol~line ~q3med from 4-hy&oxypmline was effectively methylat~ by a Gilman reagent to afford a 4-mcthyl-3,4dehydmpmline di~rivative. Then,
โฆ LIBER โฆ
ChemInform Abstract: Stereoselective Deuterium-Labeling of Diastereotopic Methyl and Methylene Protons of L-Leucine.
โ Scribed by M. OBA; T. TERAUCHI; A. MIYAKAWA; H. KAMO; K. NISHIYAMA
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 36 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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