✦ LIBER ✦
ChemInform Abstract: Stereocontrolled Syntheses of Novel Styryl Lactones, (+)-Goniodiol, (+)-Goniotriol, (+)-8-Acetylgoniotriol, (+)-Goniofufurone, (+)-9-Deoxygoniopypyrone, (+)-Goniopypyrone, and (+)-Altholactone from Common Intermediates and Cytotoxicity of Their Congeners.
✍ Scribed by Masayoshi Tsubuki; Kazuo Kanai; Hiromasa Nagase; Toshio Honda
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 34 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Stereocontrolled Syntheses of Novel Styryl Lactones, (+)-Goniodiol, (+)-Goniotriol, (+)-8-Acetylgoniotriol, (+)-Goniofufurone, (+)-9-Deoxygoniopypyrone, (+)-Goniopypyrone, and (+)-Altholactone from Common Intermediates and Cytotoxicity of Their Congeners.
-The title lactones except goniofufurone (VII) are marginally cytotoxic. Some congeners like (IV) and (V) inhibit cell growth better than the natural lactones.