Treatment of salts 1a-b with Grignard reagents gives, after reduction of the resulting unstable dihydropyridines 7, the tetrahydropyridines 8a-c, with modest selectivities but in very few steps and under practical conditions. Higher stereoand regioselectivities are obtained with salt 1c which gives
ChemInform Abstract: Stereocontrolled Alkylation of Chiral Pyridinium Salt Toward a Short Enantioselective Access to 2-Alkyl- and 2,6-Dialkyl-1,2,5,6-tetrahydropyridines.
โ Scribed by Berangere Guilloteau-Bertin; Delphine Compere; Laurent Gil; Christian Marazano; Bhupesh C. Das
- Publisher
- John Wiley and Sons
- Year
- 2001
- Weight
- 37 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0931-7597
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โฆ Synopsis
Abstract
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a โFull Textโ option. The original article is trackable v