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ChemInform Abstract: Some Benzenesulfonamido-Substituted Valerophenones that are Selective Antagonists for the 5-HT2c Receptor.

✍ Scribed by K. K. WEINHARDT; D. W. BONHAUS; A. DE SOUZA

Publisher: John Wiley and Sons
Year: 2010
Weight: 31 KB
Volume: 28
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199715148

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✦ Synopsis

Some Benzenesulfonamido-Substituted Valerophenones that are Selective Antagonists for the 5-HT2c Receptor. -Benzenesulfonamides of the new type (VII) show good 5-HT-receptor binding affinity, especially for the 5-HT2c-subtype. The derivative ( VIIc) proved to be more selective than other known compounds; the pharmacological profile of this derivative will be published (no yields given). -(WEINHARDT, K. K.; BONHAUS, D. W.;

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