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ChemInform Abstract: Solution and Soluble Polymer Syntheses of 3-Aminoimidazoline-2,4-diones.

โœ Scribed by Juyoung Yoon; Chang-Woo Cho; Hyunsoo Han; Kim D. Janda

Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
30
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Solid-Phase Synthes
ChemInform Abstract: Solid-Phase Synthesis of Chiral 3-Substituted Quinazoline-2,4-diones.
โœ L. GOUILLEUX; J.-A. FEHRENTZ; F. WINTERNITZ; J. MARTINEZ ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 29 KB ๐Ÿ‘ 1 views

Solid-Phase Synthesis of Chiral 3-Substituted Quinazoline-2,4-diones. -A series of N-urethane precursors such as (I) or (III) are prepared and subjected to cyclization in the presence of base (DBU, NaOH or NEt3). The desired quinazolines are obtained in good to excellent yield without racemization.