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ChemInform Abstract: Soluble Polyethylene Glycol Supports for Liquid-Phase Combinatorial Synthesis

✍ Scribed by D. J. GRAVERT; K. D. JANDA

Publisher
John Wiley and Sons
Year
2010
Weight
24 KB
Volume
29
Category
Article
ISSN
0931-7597

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The choice of a polymeric support is a key factor for the success of solid-phase methods for syntheses of organic compounds and biomolecules such as peptides and oligonucleotides. Classical Merrifield solid-phase peptide synthesis (SPPS), performed on low cross-linked hydrophobic polystyrene (PS) be