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ChemInform Abstract: Solid-Phase Synthesis of Phosphorylated Tyr-Peptides by “Phosphite Triester” Phosphorylation

✍ Scribed by M. W. PENNINGTON


Book ID
112021921
Publisher
John Wiley and Sons
Year
2010
Weight
23 KB
Volume
26
Category
Article
ISSN
0931-7597

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Synthesis of Tyr(P)-containing peptides
✍ John W. Perich 📂 Article 📅 1996 🏛 Springer Netherlands 🌐 English ⚖ 418 KB

A novel method for the efficient synthesis of Tyr(P)-containing peptides is described by the 'phosphite-triester' phosphorylation of the tyrosine residue after its incorporation into the peptide chain. In this approach, the peptide resin is assembled by Fmoc solid-phase peptide synthesis (PyBOP ® co